Genetic Disorders :: essays research papers

Each year a number of children are born with biological defects that impair normal function. For THREE of the following conditions, discuss such aspects as the biological cause, the methods of treatment and possible means of detection and/or prevention.One lethal disorder inherited as a recessive allele is Tay-Sachs disease. This is caused by a dysfunctional enzyme that fails to break down brain lipids of a certain class. The symptoms usually become manifest a few months after birth. Some symptoms are seizures, blindness and degeneration of motor and mental performance. Death is the result of this disease, in children. With Tay-Sachs disease, the brain cells of a baby are unable to metabolize gangliosides, a type of lipid, because a crucial enzyme does not work properly. As the lipids accumulate in the brain, the brain cells gradually cease to function normally. Only children who inherit two copies of the Tay-Sachs allele qualifies as a recessive. At the biochemical level, we observe an intermediate phenotype characteristic of incomplete dominance: The enzyme deficiency that causes Tay Sachs disease can be detected in heterozygotes, who have an activity level of the lipid-metabolizing enzyme that is intermediate between individuals homozygous for the normal allele and individuals with Tay-Sachs disease. Heterozygotes lack symptoms of the disease, apparently because half the normal amount of functional enzyme is sufficient to prevent lipid accumulation in the brain. In fact, heterozygous individuals produce equal numbers of normal and dysfunctional enzyme molecules. At the molecular level, the normal allele and the Tay-Sachs allele are codominant. Sickle-cell disease is caused by the substitution of a single amino acid in the hemoglobin protein of red blood cells. When the oxygen content of an affected individual’s blood is low, the sickle-cell hemoglobin deforms the red cells to a sickle shape. Sickling of the cells, in turn, can lead to other symptoms. The multiple effects of a double dose of the sickle-cell allele exemplify pleiotropy, which is the ability of a gene to affect an organism in many ways. Regular blood transfusions could be used to ward off brain damage in children with sickle-cell disease. Heterozygotes with the sickle-cell allele may suffer some symptoms of the disease when there is a reduction of blood oxygen. Since the two alleles are codominant at the molecular level; both normal and abnormal hemoglobins are made. Only individuals who are homozygous for the sickle-cell allele suffer from the disease.

Challenges In Our Life Essay

Good Morning fellow students and teachers. Journey is a vital aspect in our lives. Everyone in here will encounter a type of journey whether it’s physical, imaginative or inner, They happen to everyone, whether we want it or not. Life itself is a journey with many challenges to overcome, with many experiences to learn from and with many opportunities to explore. Journeys allow us to grow, to become wiser, and to look at life from a different perspective. As you can see in the stimulus Image, many challenges arise when going through a personal journey, we are unexpected of the challenges, we must overcome obstacles, we must face these challenges even though they might be seen impossible to over whelm. Today’s speech will focus on two different journeys, one from Louis Nowra’s comic play, ‘Cosi’ and the other from Ben Stiller’s movie, ‘The Secret life of Walter Mitty’. Going through a personal journey will come with many challenges to overcome, whether it be big or small. It might be difficult to overcome let alone maintaining the shock of the challenge. The Attitudes of others may implement the difficulty of overcoming that challenge. Nowra’s Cosi shows a good example of this Challenge in Act two, Scene two. Lewis and Lucy are seen arguing about the play, Lewis did not want to attend the Galileo rehearsals nor did he want to attend the moratorium meeting. As both of them are seen arguing, Lucy tells lewis that she has been having an affair with Nick. Lewis is Stunned at this news. Lucy excuse is that she has sex with Nick, but sleeps with Lewis. In this scene, lewis has reached a personal growth in his journey, wanting to rehearse the Cosi Fan Tutte play rather than going to the Galileo rehearsals and the moratorium meeting. However, this scene comes with a challenge in his journey. Lewis is stunned, just learned that his girlfriend just had an affair with his best friend. Lucy lack of respect for Lewis’s feeling and justifies with a cruel excuse ‘I have sex with him and sleep with you’. Nowra enables us to see Lucy herself can never make a personal journey. Lewis’s feeling is seem hurt for the lack of respect from Lucy, Lewis is seen angry but recites a line from the play, ‘Women’s constancy is like the Arabian Phoenix. Everyone swears it exists, but no one has seen it’. Lucy is seen angry from this quote and curses at Lewis for even mentioning the play. The Lack of respect Lucy has towards lewis shows us how overcoming a challenge can be very hard let alone someone  else affecting the challenge making the challenge itself seem impossible to overcome. ‘Life is about courage and going into the unknown’, going into the unknown is a journey that will come with challenges, these challenges will push us out of our conform zone. Walter Mitty works for Life magazine, which is going through a transition into the online scene, meaning his job is on the line. Walter Mitty is seen as character with a dull life, not really doing anything noteworthy. While Walter is a negative assets manger, he must find the the last photo that will be in the cover of the last publish magazine. Walter Mitty has never really experienced life, never been to the unknown, however, his seemingly last mission will force him to go outside his comfort zone and experience reality, as he has never done before. Walter Mitty embarks a mission to find his last photo the company will ever publish, he will be force to stop his daily dreaming, and face reality. His daily job consist of him staying in a dark basement, but his adventures spiral from booking a last-minute flight to Greenland to near-fatal bouts with volcanoes, sharks and jumping out of a helicopter in the middle of a hurricane. Through his journey and the fantastic use of picturesque scene and dreamy sounds, reflects the Walter’s inner thoughts and perspective of life through his journey. The realisation of Walter Mitty might losing his jobs, makes him realise that he has been living a dull life and goes into a journey to find himself, and explore life. His dull life turns into an adventures life making him going out of his comfort zone.

Martin Luther King Jr. s Letter From Birmingham Jail

Martin Luther King, Jr.’s, â€Å"Letter from Birmingham Jail,† emphasizes the need for civil disobedience when faced with unjust laws. This idea contradicts Socrates’ claim made in Crito, that one must follow the law under all circumstances. In this paper, I will argue that Socrates is not a proponent of civil disobedience based on King’s definition of civil disobedience and Socrates’ charges. Moreover, I will argue that both Socrates and King disagree with one another based on the concept of civil disobedience—breaking the law and rejecting certain ideals. Martin Luther King, Jr. defines civil disobedience as the act of nonviolently refusing to obey unjust laws as a form of protest, usually resulting in accepting the consequences of†¦show more content†¦He commits this nonviolent act to abolish an unjust law (Jim Crow Laws) that resonated out of harmony with his moral truths. In that case, King is a proponent of civil disobedien ce because he does not comply with what he finds as unjust and seeks action to cause change. Similarly, Socrates does not follow this definition of civil disobedience because he challenges the ‘morals’ of certain laws rather than ‘break the law’. When faced with the charges of impiety (not believing in God) and corrupting the youth, Socrates challenges these claims in court by reasoning with his own moral truths. For example, Socrates questions â€Å"Can a man believe in spiritual and divine agencies, and not in spirits or demigods?† (Apology 10) in response to his impiety charge. In other words, Socrates believes in divine things, thus he believes in divinities. The city of Athens convicts Socrates of atheism based on his premise, even though his argument for being impious does not articulate with his definition of ‘being impious’. It may seem as if Socrates questions whether these laws are just or unjust, however, Socrates does not intentionally break the law because his belief and understanding of God are different from t he rest of society. Socrates does not say he disbelieves in God, rather he interprets it differently. Definitively, Socrates is not civilly disobedience because he does not intentionally break the law, rather heShow MoreRelatedMartin Luther King Jr. s Letter From A Birmingham Jail1157 Words   |  5 PagesMartin Luther King Jr.’s â€Å"Letter from a Birmingham Jail† is directed towards the clergymen, although America is his audience, King had come to Birmingham to address the segregation problem in the United States. He refuses to stay silent, even though people told him to wait for the change to happen. King is a part of the Southern Christian Leadership Conference that has many organizations across the South. He felt that he has a right to be in Birmingham because his organizations have connections withRead MoreMartin Luther King Jr. s Letter From Birmingham Jail934 Words   |  4 PagesIn Martin Luther King Jr.’s , â€Å" Letter from Birmingham Jail†, King responds to the judgments of a group of clergymen , after King s arrest, by writing a letter explaining why the clergymen s judgments were wrong. In his letter, king brings very reasonable and valid points that challenge the judgments of the ministers. The main arguments that king makes would be the reason of his existence in Birmingham, white power structure and its racial injustice, and finally why negotiation has brought up impatienceRead MoreMartin Luther King Jr s Letter From Birmingham Jail1665 Words   |  7 Pagesbetween these two are most evident in their desire for freedom. Martin Luther King Jr. wanted freedom from segregation and Plato wanted freedom from ignorance. They both wanted justice, and knew that it was immoral to take deny another being justice. For example, Plato has said, â€Å"†¦ Injustice is always an evil and dishonor to him who acts unjustly.† This is similar to what Martin Luther King Jr has also stated in â€Å"Letters from Birmingham Jail†, â€Å"We have a moral responsibility to disobey any law that conflictsRead MoreMartin Luther King Jr.s Letter From Birmingham Jail1726 Words   |  7 PagesOver the course of Letter from Birmingham Jail (1963), the author, Martin Luther King Jr., makes extended allusions to multiple philosophers, among them Aquinas and Socrates. His comparison would seem to indicate that he shares an affinity with them. However, the clarity with which he makes his arguments and the dedication to a single premise strikes most strongly of Kant. Just as Kant’s magnum opus, Critique of Pure Reason, attempted to completely upend a previously accepted mode of thought, soRead MoreMartin Luther King Jr.s Letter From Birmingham Jail890 Words   |  4 PagesFrom 1882-1968, 4,743 lynchings occurred in the United States (NAACP). African Americans accounted for 72.2% of recorded lynchings, yet close to none of these lynchings were ever brought justice. Racial injustice was a huge issue until the mid-l ate twentieth century, and Martin Luther King Jr.’s 1963 â€Å"Letter from Birmingham Jail† was one of the first documents to address the issue. It is one of history’s most important documents regarding racial injustice, as it is considered a classic documentRead MoreMartin Luther King Jr.’S Persuasion in â€Å"Letter from Birmingham Jail†1569 Words   |  7 PagesMartin Luther King Jr.’s Persuasion in â€Å"Letter From Birmingham Jail† After being arrested and imprisoned in Birmingham Jail, Martin Luther King Jr. wrote one of his most famous works to the people of Birmingham, titled â€Å"Letter From Birmingham Jail on April 16, 1963. This piece speaks of the evils of the segregation laws and how the blacks had been treated unfairly in Birmingham, in an attempt to get the white people to support the desegregation of Birmingham. He had been imprisoned because of hisRead MoreMartin Luther King Jr.’s Letter from Birmingham Jail Essay1266 Words   |  6 PagesPower Analysis: Martin Luther King Jr.’s Letter from Birmingham Jail A statement from eight white clergymen from Alabama prompted Martin Luther King’s â€Å"Letter From Birmingham Jail†. This statement criticized Kings actions of non-violent protests against racial segregation and the injustice of unequal civil rights in America (Carpenter elt al.). The eight clergymen considered Birmingham to be â€Å"their† town and King was disrupting the â€Å"Law and Order and Common Sense† established in coping with racialRead MoreAnalysis Of Martin Luther King Jr s Letter From Birmingham Jail986 Words   |  4 Pages and Dr. Martin Luther King Jr’s Letter from Birmingham Jail are two important pieces of history. In Lincoln’s speech he speaks about the dangers of slavery in the United States and warned everybody that people who disrespected American laws could destroy the United States. On the other hand, Martin Luther King Jr. defended the strategy of nonviolent resistance to racism, and argued that people have a mora l responsibility to break unjust laws. Based on these facts, Martin Luther King Jr does notRead MoreAnalysis of Martin Luther King Jr.s Letter from Birmingham Jail962 Words   |  4 Pagesintangible, it is still necessary. Some forms of inspiration come as passionate love while others appeal as injustice. Martin Luther King Jr.s Letter from Birmingham Jail was a response to A Call for Unity by eight white clergymen. His inspiration for writing the letter was the clergymens unjust proposals and the letter allowed him to present his rebuttal. Martin Luther King Jr. effectively crafted his counter argument by first directly addressing his audience, the clergymen, and then using logosRead More Martin Luther King Jr.s Letter from Birmingham Jail Essay1149 Words   |  5 PagesMartin Luther King Jr.s Letter from Birmingham Jail   Ã‚  Ã‚  Ã‚  Ã‚  Martin Luther King Jr. writes the Clergymen that have written him a letter disputing his actions in Birmingham. King is disturbed and offended by the Clergymen disagreeing with his purpose in Birmingham. King say he normally does not respond to criticism because it would waste to much precious time, but since these were men of good will he wanted to give his answers to their statements. In Kings letter he appeals to many emotions as Martin Luther King Jr. s Letter From Birmingham Jail In Martin Luther King Jr.’s , â€Å" Letter from Birmingham Jail†, King responds to the judgments of a group of clergymen , after King s arrest, by writing a letter explaining why the clergymen s judgments were wrong. In his letter, king brings very reasonable and valid points that challenge the judgments of the ministers. The main arguments that king makes would be the reason of his existence in Birmingham, white power structure and its racial injustice, and finally why negotiation has brought up impatience and little to no solutions. The overall structure of King’s letter was well organized and the letter delivered valid explanations as to why the clergymen s judgments were wrong and why it is that action had to be taken in order to grasp the attention needed to settle the conflicts of racial injustice the black community in Birmingham was facing. King begins his letter by pointing out how the ministers referred to his actions as â€Å"untimed† and â€Å"unwisely† meaning that they were not smart and were done at a wrong time, king also points out that he was referred to as an â€Å"outsider† (601). After making it clear to the clergymen that he only wants to give an explanation as to why their statements are wrong, he begins to respond to his existence and why he shouldn’t be considered an outsider. King gives four major reason, the first reason being that king had organizational ties in Birmingham, he points out that he has,† the honor of serving as the president of the SouthernShow MoreRelatedMartin Luther King Jr. s Letter From A Birmingham Jail1157 Words   |  5 PagesMartin Luther King Jr.’s â€Å"Letter from a Birmingham Jail† is directed towards the clergymen, although America is his audience, King had come to Birmingham to address the segregation problem in the United States. He refuses to stay silent, even though people told him to wait for the change to happen. King is a part of the Southern Christian Leadership Conference that has many organizations across the South. He felt that he has a right to be in Birmingham because his organizations have connections withRead MoreMartin Luther King Jr. s Letter From Birmingham Jail1223 Words   |  5 PagesMartin Luther King, Jr.’s, â€Å"Letter from Birmingham Jail,† emphasizes the need for civil disobedience when faced with unjust laws. This idea contradicts Socrates’ claim made in Crito, that one must follow the law under all circumstances. In this paper, I will argue that Socrates is not a proponent of civil disobedience based on King’s definition of civil disobedience and Socrates’ charges. Moreover, I will argue that both Socrates and King disagree with one another based on the concept of civilRead MoreMartin Luther King Jr s Letter From Birmingham Jail1665 Wo rds   |  7 Pagesbetween these two are most evident in their desire for freedom. Martin Luther King Jr. wanted freedom from segregation and Plato wanted freedom from ignorance. They both wanted justice, and knew that it was immoral to take deny another being justice. For example, Plato has said, â€Å"†¦ Injustice is always an evil and dishonor to him who acts unjustly.† This is similar to what Martin Luther King Jr has also stated in â€Å"Letters from Birmingham Jail†, â€Å"We have a moral responsibility to disobey any law that conflictsRead MoreMartin Luther King Jr.s Letter From Birmingham Jail1726 Words   |  7 PagesOver the course of Letter from Birmingham Jail (1963), the author, Martin Luther King Jr., makes extended allusions to multiple philosophers, among them Aquinas and Socrates. His comparison would seem to indicate that he shares an affinity with them. However, the clarity with which he makes his arguments and the dedication to a single premise strikes most strongly of Kant. Just as Kant’s magnum opus, Critique of Pure Reason, attempted to completely upend a previously accepted mode of thought, soRead MoreMartin Luther King Jr.s Letter From Birmingham Jail890 Words   |  4 PagesFrom 1882-1968, 4,743 lynchings occurred in the United States (NAACP). African Americans accounted for 72.2% of recorded lynchings, yet close to none of these lynchings were ever brought justice. Racial injustice was a huge issue until the mid-l ate twentieth century, and Martin Luther King Jr.’s 1963 â€Å"Letter from Birmingham Jail† was one of the first documents to address the issue. It is one of history’s most important documents regarding racial injustice, as it is considered a classic documentRead MoreMartin Luther King Jr.’S Persuasion in â€Å"Letter from Birmingham Jail†1569 Words   |  7 PagesMartin Luther King Jr.’s Persuasion in â€Å"Letter From Birmingham Jail† After being arrested and imprisoned in Birmingham Jail, Martin Luther King Jr. wrote one of his most famous works to the people of Birmingham, titled â€Å"Letter From Birmingham Jail on April 16, 1963. This piece speaks of the evils of the segregation laws and how the blacks had been treated unfairly in Birmingham, in an attempt to get the white people to support the desegregation of Birmingham. He had been imprisoned because of hisRead MoreMartin Luther King Jr.’s Letter from Birmingham Jail Essay1266 Words   |  6 PagesPower Analysis: Martin Luther King Jr.’s Letter from Birmingham Jail A statement from eight white clergymen from Alabama prompted Martin Luther King’s â€Å"Letter From Birmingham Jail†. This statement criticized Kings actions of non-violent protests against racial segregation and the injustice of unequal civil rights in America (Carpenter elt al.). The eight clergymen considered Birmingham to be â€Å"their† town and King was disrupting the â€Å"Law and Order and Common Sense† established in coping with racialRead MoreAnalysis Of Martin Luther King Jr s Letter From Birmingham Jail986 Words   |  4 Pages and Dr. Martin Luther King Jr’s Letter from Birmingham Jail are two important pieces of history. In Lincoln’s speech he speaks about the dangers of slavery in the United States and warned everybody that people who disrespected American laws could destroy the United States. On the other hand, Martin Luther King Jr. defended the strategy of nonviolent resistance to racism, and argued that people have a mora l responsibility to break unjust laws. Based on these facts, Martin Luther King Jr does notRead MoreAnalysis of Martin Luther King Jr.s Letter from Birmingham Jail962 Words   |  4 Pagesintangible, it is still necessary. Some forms of inspiration come as passionate love while others appeal as injustice. Martin Luther King Jr.s Letter from Birmingham Jail was a response to A Call for Unity by eight white clergymen. His inspiration for writing the letter was the clergymens unjust proposals and the letter allowed him to present his rebuttal. Martin Luther King Jr. effectively crafted his counter argument by first directly addressing his audience, the clergymen, and then using logosRead More Martin Luther King Jr.s Letter from Birmingham Jail Essay1149 Words   |  5 PagesMartin Luther King Jr.s Letter from Birmingham Jail   Ã‚  Ã‚  Ã‚  Ã‚  Martin Luther King Jr. writes the Clergymen that have written him a letter disputing his actions in Birmingham. King is disturbed and offended by the Clergymen disagreeing with his purpose in Birmingham. King say he normally does not respond to criticism because it would waste to much precious time, but since these were men of good will he wanted to give his answers to their statements. In Kings letter he appeals to many emotions as